Back in her high school days Jeon Seol-Hee (Kim Jung-Eun) was the singer for a legendary rock group, but to support her younger sister's education she started to work as a clerk at a top Korean law firm. While working there she met a bright lawyer named Cha Ji-Wook (Kim Seung-Su) and eventually married. Seol-Hee then became the daughter-in-law for an ultra wealthy family, but Seol-Hee soon learns that all that glitters isn't gold.

At social functions Seol-Hee's husband instructs her to not speak and just nod in agreement with the others. Her mother-in-law (Cha Hwa-Yeon) is incredibly insensitive to Seol-Hee as a person. What pushes Seol-Hee to the edge is when Seol-Hee's younger sister, who is now a doctor, is hospitalized with cancer and needs a bone marrow transplant from Seol-Hee. Seol-Hee's mother-in-law opposes Seol-Hee doing the medical procedure because it will interfere with Seol-Hee's visits to a fertility clinic. Seol-Hee's husband offers no support whatsoever. A few days later at a family dinner, Seol-Hee announces that she will file for divorce.

Seol-Hee, now single again, embarks on a new career as a singer for the "Madonna Band," an all female group consisting of "ahjummas" (older women). Seol-Hee also starts a relationship with Jang Tae-Hyeon (Lee Jun-Hyuk), a guitarist and composer ...