Jane Got a Gun centers on Jane Hammond, who has built a new life with her husband Bill "Ham" Hammond after being tormented by the ultra-violent Bishop Boys outlaw gang. She finds herself in the gang's cross-hairs once again when Ham stumbles home riddled with bullets after dueling with the Boys and their relentless mastermind Colin. With the vengeful crew hot on Ham's trail, Jane has nowhere to turn but to her former fiancé Dan Frost for help in defending her family against certain destruction. Haunted by old memories, Jane's past meets the present in a heart-stopping battle for survival.